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We give a probabilistic powerdomain construction on the category of inductively complete partial orders; it is the partial order of continuous [0, 11-valued evaluations on the Scott topology. By means of a theory of integration with respect to such evaluations, the power-domain is shown to be a monad, and indeed one gets a model for Moggi's computational(More)
Searches for the neutral Higgs bosons h 0 and A 0 are used to obtain limits on the Type II Two Higgs Doublet Model (2HDM(II)) with no CP–violation in the Higgs sector and no additional particles besides the five Higgs bosons. The analysis combines approximately 170 pb −1 of data collected with the OPAL detector at √ s ≈ 189 GeV with previous runs at √ s ≈ m(More)
  • G Abbiendi, K Ackerstaff, +141 authors Heisenberg Fellow
  • 1999
Cross-sections and angular distributions for hadronic and lepton pair final states in e + e − collisions at a centre-of-mass energy near 189 GeV, measured with the OPAL detector at LEP, are presented and compared with the predictions of the Standard Model. The results are used to measure the energy dependence of the electromagnetic coupling constant α em ,(More)
A1 adenosine receptors were labeled in rat brain sections with the antagonist [3H]8-cyclopentyl-1,3-dipropylxanthine ([3H]DPCPX) and visualized at the light microscopic level using autoradiography. The specific binding of [3H]DPCPX to the sections showed the pharmacological characteristics of A1 adenosine receptors and was accompanied by very low levels of(More)
Putative receptors for endothelin were localised autoradiographically in frozen sections of rat and human brain using [125I]endothelin as a ligand. In the rat brain the highest densities were in the granular layer of the cerebellum, choroid plexus, hippocampus, and habenular nucleus. Similar brain high densities were found in the human cerebellum and(More)
This chapter reviews the current classification of adrenoceptors, and notes the difficulties of combining the molecular biological and pharmacological classifications of adrenoceptors. Possibilities for mapping the distribution of the proposed subtypes of adrenoceptors using currently available ligands are discussed, and the autoradiographic visualisation(More)
OBJECTIVE To investigate the excitability of segmental and suprasegmental systems in patients with primary restless legs syndrome (pRLS) by measuring the cortical silent period (C-SP) and the peripheral silent period (P-SP). BACKGROUND There is some evidence that RLS may be the motor manifestation of normal CNS periodicity that becomes disinhibited under(More)
The determination of accurate NOE-derived interproton distances and confirmation/prediction of relative populations in multi-conformer, flexible small molecules was investigated with the model compound 4-propylaniline. The low accuracy assumed for semi-quantitative NOE distance restraints is typically taken to suggest that large numbers of constraints need(More)
A1-adenosine receptors were identified in sections of rat brain and guinea pig kidney with the radioiodinated agonist 125I-N6-p-hydroxyphenylisopropyladenosine (125I-HPIA) using in vitro autoradiography. The affinities of adenosine receptor ligands in competing with 125I-HPIA binding to tissue sections were in good agreement with those found in membranes,(More)