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  • C. Isaacson
  • South African medical journal = Suid-Afrikaanse…
  • 1977
All autopsies on Black patients who died of heart disease at Baragwanath Hospital were examined for the years 1959, 1960 and 1976. The commonest form of heart disease encountered in South African Blacks is undoubtedly hypertensive heart disease and by far the majority of these cases are of essential hypertension. There appears to have been a slight rise in(More)
The change of the staple diet of Black South Africans from sorghum to maize (corn) is the cause of the epidemic of squamous carcinoma of the oesophagus. For many years sorghum was the staple diet of Black South Africans. From approximately the early part of the twentieth century, maize gradually replaced sorghum. Squamous carcinoma of the oesophagus was(More)
Skin-lightening preparations containing hydroquinone are used extensively by black South Africans. In some instances these preparations produce severe and irreversible cutaneous damage. Clinically, the deleterious effects begin with darkening and coarsening of the skin, followed by a hyperpigmented papular condition. Histologically, there is increased(More)
In a series of 115 black patients admitted to a chronic haemodialysis programme over a 4-year period, a definitive pathological diagnosis was made in 70 cases. Of these, 5 were made anatomically while in 65 the diagnosis was histological. The commonest single cause of end-stage renal disease was essential malignant hypertension which showed a peak incidence(More)
Primary squamous cell carcinoma of the liver has previously been reported to arise only from the lining of a developmental hepatic cyst or in a hepatic teratoma. The authors describe the occurrence of such a tumor in association with multiple intrahepatic cholesterol gallstones. It is suggested that the gallstones may have caused squamous metaplasia of the(More)