C G Gaitatzes

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PURPOSE The goal of this study was to evaluate the effect of oxygen deprivation on rhodopsin regeneration in the excised mouse eye. METHODS A new preparation for studying rhodopsin regeneration with a superfused excised albino mouse eye was developed. The preparation exhibits multiple regenerations after moderate bleaches (15%-20%) and is sensitive to the(More)
PURPOSE To evaluate the effect of diabetes on rhodopsin regeneration in the excised mouse eye. METHODS A superfused excised mouse eye preparation that exhibits rhodopsin regeneration after moderate bleaches and that is responsive to the composition of the perfusate was used. Diabetes was induced in albino mice (BALB/c) with the diabetogenic agent(More)
To study the process of rhodopsin regeneration a superfused excised whole eye preparation of the albino mouse was developed. With this preparation, complete regeneration could be observed after each of the first two illuminations (bleaching 15-20%), and incomplete regeneration after a third illumination. Regeneration was minimal at extracellular glucose(More)
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