C. G. G. Aitken

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Translation initiation in eukaryotes begins with the formation of a pre-initiation complex (PIC) containing the 40S ribosomal subunit, eIF1, eIF1A, eIF3, ternary complex (eIF2-GTP-Met-tRNAi), and eIF5. The PIC, in an open conformation, attaches to the 5' end of the mRNA and scans to locate the start codon, whereupon it closes to arrest scanning. We present(More)
Evaluation of trace evidence for three-level multivariate data with the use of graphical models. Abstract The evaluation of measurements on characteristics of trace evidence found at a crime scene and on a suspect is an important part of forensic science. There are commonly three levels of variation in such evidence. First, there is measurement error on the(More)
At present, likelihood ratios for two-level models are determined with the use of a normal kernel estimation procedure when the between-group distribution is thought to be non-normal. An extension is described for a two-level model in which the between-group distribution is very positively skewed and an exponential distribution may be thought to represent a(More)
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