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Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous identity, interaction with the surrounding stroma and tissues, hierarchic network formation, and recruitment of pericytes. Notch receptors and ligands (Jagged and Delta-like) play a critical role in this process in addition to VEGF.(More)
Neo-blood vessel growth (angiogenesis), which may involve the activation of pre-existing endothelial cells (EC) and/or the recruitment of bone marrow-derived vascular precursor cells (BM-VPC), is essential for tumor growth. Molecularly, besides the well established roles for Vascular endothelial growth factor (VEGF), recent findings show the Notch(More)
We introduce a method for constructing an element-by-element sparse approximate inverse (SAI) preconditioner designed to be effective in a massively-parallel spectral element modeling environment involving non-symmetric systems. This new preconditioning approach is based on a spectral optimization of a low-resolution pre-conditioned system matrix (PSM). We(More)
STATEMENT OF PROBLEM Conventional diamond burs show several limitations such as the heterogeneity of grain shapes, the difficulty of automation during fabrication, the decrease of cutting effectiveness due to repeated sterilization, and short lifetime. An additional shortcoming may be represented by the potential release of Ni+2 ions from the metallic(More)
Background: auditory temporal processing. Aim: to compare the performance of children in auditory temporal processing tests according to different temporal variables such as inter-stimulus interval, stimuli duration and type of task (discrimination or ordering). Method: 27 children, with ages between 9 to 12 years, were evaluated. In order to analyze the(More)
PURPOSE To compare the efficacy of 3 different artificial tears (AT) acting primarily in one of the 3 tear film layers (Tears Again®, lipidic; Opticol®, aqueous; Optive®, mucin) in recovering the tear film changes in patients with dry eye symptoms due to external causes. METHODS A total of 27 patients, with dry eye symptoms associated with extra hours of(More)
We utilized a microwave plasma reactor based on a surface-wave-sustained discharge for uniform coating of fused silica windows with polycrystalline diamond films. Grain size and average roughness as small as 30 and 2.2 nm, respectively, were obtained, resulting in a uniform loss of transparency of only 10% over the 190-800-nm band for as-deposited(More)
Recurrent tracheoesophageal fistula in children is a challenging issue, associated to high morbidity and mortality, due to major scarring and inflammatory changes resulting from previous interventions and the disease itself. Most cases require surgical treatment, but the complexity of the situation may, sometimes, prevent the traditional approach by(More)
A 6-month-old girl with Beckwith-Wiedemann syndrome, multiple haemangiomas (axillary, laryngeal, pulmonary and hepatic) and diaphragmatic eventration was reported. All tumours responded to treatment with propranolol. The surgical correction of diaphragmatic eventration was crucial to a better outcome.
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