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Eucaryotic organisms respond to elevated environmental temperatures by rapidly activating the expression of heat shock genes. The transcriptional activation of heat shock genes is mediated by a conserved upstream regulatory sequence, the heat shock element (HSE). Using an HSE-binding assay, we show that a cellular factor present in a range of vertebrate(More)
BACKGROUND The aetiology of food allergy remains unclear. Although failure to develop or breakdown in oral tolerance has been proposed, the existence of physiologic sensitization routes other than the gastrointestinal tract cannot be excluded. OBJECTIVE The purpose of this study is to clarify whether or not exposure to allergen through the skin can(More)
A new preamplifier for suppressing low-frequency interference is presented. The proposed preamplifier, with its front end being implemented by an instrumentation amplifier, enjoys the following advantages: differential high-pass filtering, high input impedance, high common--mode rejection ratio and low passive sensitivity. This circuit can be realized with(More)
Here we review different aspects of the protein folding literature. We present a broad range of observations, showing them to be consistent with a general hierarchical protein folding model. In such a model, local relatively stable, conformationally fluctuating building blocks bind through population selection, to yield the native state. The model includes(More)
Viscoelastic materials are known to exhibit temporal response that changes force or displacement at the contact interface under position or force control, respectively. In this paper, we conduct experimental study using force control to explore and observe creep phenomenon in robotic grasping in order to better understand the nature of such contact(More)
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