César Marquez

Learn More
β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neurites in a variety of assays, but the mechanism by which APP performs this function is not(More)
This paper presents the architecture and circuit design of a single chip 32 mm<sup>2</sup> 90 nm CMOS DSP transceiver for electronic dispersion compensation (EDC) of multimode fibers at 10 Gb/s, based on maximum likelihood sequence detection (MLSD). This is the first MLSD-based transceiver for multimode fibers and the first fully integrated DSP based(More)
A key interest in clinical diagnosis and pharmaceutical industry is to have a repertoire of noninvasive biomarkers to—individually or in combination—be able to infer or predict the degree of liver injury caused by pathological conditions or drugs. Metabolomics—a comprehensive study of global metabolites—has become a highly sensitive and powerful tool for(More)
The factors affecting host-guest complexation between the molecular container compound cucurbit[6]uril (CB6) and various guests in aqueous solution are studied, and a detailed complexation mechanism in the presence of cations is derived. The formation of the supramolecular complex is studied in detail for cyclohexylmethylammonium ion as guest. The kinetics(More)
The desolvating droplets of EESI were used as microreactor for the mass spectrometric study of short-lived transients of reactions in condensed liquid phase in the millisecond time region. The electron-transfer-catalyzed dimerization of trans-anethole was investigated and the intermediates in the radical cation chain reaction were isolated and characterized(More)
The mechanism of reactions in solution can be studied using electrospray ionization mass spectrometry (ESI-MS). We recently conducted an ESI-MS study on the aldol reaction catalyzed by l-proline where we were able not only to follow the reaction over time, but to isolate and characterize all the reaction intermediates by tandem mass spectrometry (MS/ MS).(More)
[reaction: see text] The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by nucleotides has been studied. The quenching mechanism was analyzed on the basis of deuterium isotope effects, tendencies for exciplex formation, and the quenching efficiency in the presence of a molecular container (cucurbit[7]uril). Exciplex-induced quenching(More)