Cécile V. Denis

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Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity.

Malik Khelfaoui, Cécile V. Denis, +10 authors Pierre Billuart
The Journal of neuroscience : the official…
2007

Loss of oligophrenin1 (OPHN1) function in human causes X-linked mental retardation associated with cerebellar hypoplasia and, in some cases, with lateral ventricle enlargement. In vitro studies… (More)

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

Patrick Andre, K. S. Srinivasa Prasad, +5 authors Denisa D Wagner
Nature Medicine
2002

CD40L, a member of the tumor necrosis factor family of ligands, plays a major role in immune responses via its receptor, CD40. Recently, CD40L has been detected on the surfaces of activated platelets… (More)

P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Expressed on Platelets and Can Mediate Platelet–Endothelial Interactions in Vivo

Paul S Frenette, Cécile V. Denis, +6 authors Denisa D Wagner
The Journal of experimental medicine
2000

The platelet plays a pivotal role in maintaining vascular integrity. In a manner similar to leukocytes, platelets interact with selectins expressed on activated endothelium. P-selectin glycoprotein… (More)

Parallel Loss of Hippocampal LTD and Cognitive Flexibility in a Genetic Model of Hyperdopaminergia

Elise Morice, Jean-marie Billard, +5 authors Marika Nosten-Bertrand
Neuropsychopharmacology
2007

Dopamine-mediated neurotransmission has been implicated in the modulation of synaptic plasticity and in the mechanisms underlying learning and memory. In the present study, we tested different forms… (More)

Of von Willebrand factor and platelets

Marijke Bryckaert, J. T. Rosa, Cécile V. Denis, Peter J Lenting
Cellular and Molecular Life Sciences
2014

Hemostasis and pathological thrombus formation are dynamic processes that require multiple adhesive receptor-ligand interactions, with blood platelets at the heart of such events. Many studies have… (More)

The Clearance Mechanism of Chilled Blood Platelets

Karin M. Hoffmeister, Thomas W. Felbinger, +7 authors John H. Hartwig
Cell
2003

Platelet transfusion is a very common lifesaving medical procedure. Not widely known is the fact that platelets, unlike other blood cells, rapidly leave the circulation if refrigerated prior to… (More)

P-selectin glycoprotein ligand 1 and beta2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor.

Ronan Pendu, Virginie Terraube, +4 authors Cécile V. Denis
Blood
2006

Von Willebrand factor (VWF) is an essential component of hemostasis. However, animal studies using VWF-deficient mice suggest that VWF may also contribute to inflammation. In the present study, we… (More)

Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background.

Elise Morice, Cécile V. Denis, Bruno Giros, Marika Nosten-Bertrand
The European journal of neuroscience
2004

The dopamine transporter (DAT) plays a critical role in calibrating the duration and intensity of dopamine (DA) neurotransmission. Mice in which the DAT gene has been genetically deleted exhibit… (More)

Relationship between anxiety disorders and opiate dependence--a systematic review of the literature: implications for diagnosis and treatment.

Mélina Fatséas, Cécile V. Denis, Estelle Lavie, Marc Auriacombe
Journal of substance abuse treatment
2010

Our objective was to evaluate the prevalence and temporal sequence of co-occurrence of anxiety disorders with opiate dependence in order to better define the relationship between these two disorders… (More)

Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.

Jovanka Bestebroer, Miriam J. J. G. Poppelier, +5 authors Carla J. C. de Haas
Blood
2007

Staphylococcus aureus secretes several virulence factors interfering with host-cell functions. Staphylococcal superantigen-like (SSL) proteins are a family of 11 exotoxins with structural homology to… (More)

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