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Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells.
Stem cells offer significant therapeutic promise for the treatment of ischemic disease. However, stem cells transplanted into ischemic tissue exhibit limited therapeutic efficacy due to poorExpand
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Graphene oxide flakes as a cellular adhesive: prevention of reactive oxygen species mediated death of implanted cells for cardiac repair.
Mesenchymal stem cell (MSC) implantation has emerged as a potential therapy for myocardial infarction (MI). However, the poor survival of MSCs implanted to treat MI has significantly limited theExpand
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Design of artificial extracellular matrices for tissue engineering
Abstract The design of artificial extracellular matrix (ECM) is important in tissue engineering because artificial ECM regulates cellular behaviors, including proliferation, survival, migration, andExpand
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VEGF expression in hypoxia and hyperglycemia: reciprocal effect on branching angiogenesis in epithelial-endothelial co-cultures.
Vascular endothelial growth factor (VEGF), an angiogenic factor for endothelial cells, is produced by glomerular and tubular epithelia. Using immunoelectron microscopy, VEGF expression by podocytesExpand
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Vascular patches tissue-engineered with autologous bone marrow-derived cells and decellularized tissue matrices.
Synthetic polymer vascular patches used in cardiovascular surgery have shortcomings such as thrombosis, intimal hyperplasia, calcification, infection, and no growth potential. Tissue-engineeredExpand
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Locally Delivered Growth Factor Enhances the Angiogenic Efficacy of Adipose‐Derived Stromal Cells Transplanted to Ischemic Limbs
Ischemia is a potentially fatal medical event that is associated with as many as 30% of all deaths. Stem cell therapy offers significant therapeutic promise, but poor survival followingExpand
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Iron oxide nanoparticle-mediated development of cellular gap junction crosstalk to improve mesenchymal stem cells' therapeutic efficacy for myocardial infarction.
Electrophysiological phenotype development and paracrine action of mesenchymal stem cells (MSCs) are the critical factors that determine the therapeutic efficacy of MSCs for myocardial infarctionExpand
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Dual Roles of Graphene Oxide in Chondrogenic Differentiation of Adult Stem Cells: Cell-Adhesion Substrate and Growth Factor-Delivery Carrier
Here, it is shown that graphene oxide (GO) can be utilized as both a cell-adhesion substrate and a growth factor protein-delivery carrier for the chondrogenic differentiation of adult stem cells.Expand
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Mutual effect of subcutaneously transplanted human adipose-derived stem cells and pancreatic islets within fibrin gel.
While subcutaneous tissue has been proposed as a potential site for pancreatic islet transplantation, concern remains that the microvasculature of subcutaneous tissue is too poor to supportExpand
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