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To understand molecular genetic characteristics of Korean pigs, the genetic relationships of nine pig breeds including two Korean pigs (Korean native pig and Korean wild pig), three Chinese pigs (Min pig, Xiang pig, and Wuzhishan pig), and four European breeds (Berkshire, Duroc, Landrace, and Yorkshire) were characterized from a 16-microsatellite loci(More)
The telencephalic vesicles of early human embryos and fetuses ranging from 6-18 weeks of ovulation age were subjected to correlative light and electron microscopic, immunocytochemical and Golgi analysis. The cellular events that take place during the early stages of cortical neurogenesis are characterized by the early maturation of layer I. The deployment(More)
Golgi techniques, immunofluorescence for glial fibrillary acidic (GFA) protein, and electron microscopy (EM) were used to determine the nature of radial glia in the cerebrum of human fetuses ranging from 7 to 20 weeks of ovulation age. Successful Golgi impregnation of radial fibers was achieved in fetuses 12 weeks of age and older. These fibers spanned the(More)
Recently, we reported that GM-CSF showed therapeutic effects on the spinal cord injury (SCI) in rat model possibly via its anti-apoptotic activity in the nervous system. This study investigated the molecular mechanism of its anti-apoptotic and neuroprotective effects in N2a neuroblastoma cells and in rat SCI model. GM-CSF inhibited staurosporine-induced(More)
Radial glia of the developing spinal cord were examined by Golgi, electron microscopic and immunohistochemical methods in 40 human embryos and fetuses of ovulation age 6-20 weeks. As in developing cerebrum and cerebellum, gliogenesis in the spinal cord occurs much earlier than traditionally believed. The presence of transitional forms suggests that(More)
A well-defined coagulative lesion was produced in the fronto-parietal cortex of adult rats by application of a cold probe, and the chronological sequence of events during the healing process, particularly the relationship between astroglial processes and the newly forming basal lamina (BL) and the behavior of the extracellular matrix (ECM) was examined(More)
Detailed clinical and neuropathological studies have been made in two fullterm newborn human infants who were exposed to methylmercury in utero as a result of maternal ingestion of methylmercury-contaminated bread in early phases of pregnancy. High levels of mercury were detected in various regions of the brain at autopsy. Study of the brains revealed a(More)
  • B H Choi
  • 1986
In order to assess the nature of glial fibrillary acidic protein (GFAP) immunoreactivity in the radial glia of early human fetal cerebrum, full thickness blocks from the midconvexity of the frontoparietal region of the cerebrum of 25 human fetuses ranging from ten to 20 weeks of ovulation age were studied by light and electron microscopic (EM)(More)
A cryogenic lesion was induced in the parietal cortex of neonatal rats at postnatal day 2, and the chronological sequence of cellular events during repair and reconstruction of the cortical plate examined. Serial sections of cerebra obtained at varying intervals ranging from 1 to 60 days postinjury were studied by light and electron microscopy and by(More)
The effects of methylmercuric chloride (MMC) on the rate of oxygen uptake were determined in purified cultures of oligodendrocytes, astrocytes, and cerebral cortical and cerebellar granular neurons obtained from embryonic and neonatal rat brains. Rapid and profound inhibition of oxygen uptake took place in all cell types following MMC exposure. However, the(More)