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Email overload is a growing problem for many users in the workplace [1]. Users often have trouble retrieving messages for use later or in remembering to reply or to act on a particular message. There are two causes. The first is due to the problems associated with maintenance and retrieval in a semantic hierarchical structure. The second is due to current(More)
When looking at the social phenomenon that are arise from the use of Internet communications tools, one must consider the properties of the tool that influence human-to-human interaction. This paper presents a number of such properties and discusses their importance. In addition, existing Internet communications tools are described both in general and with(More)
It remains unclear whether causal, rather than merely correlational, relationships in molecular networks can be inferred in complex biological settings. Here we describe the HPN-DREAM network inference challenge, which focused on learning causal influences in signaling networks. We used phosphoprotein data from cancer cell lines as well as in silico data(More)
Acute Myeloid Leukemia (AML) is a fatal hematological cancer. The genetic abnormalities underlying AML are extremely heterogeneous among patients, making prognosis and treatment selection very difficult. While clinical proteomics data has the potential to improve prognosis accuracy, thus far, the quantitative means to do so have yet to be developed. Here we(More)
Despite wide applications of high-throughput biotechnologies in cancer research, many biomarkers discovered by exploring large-scale omics data do not provide satisfactory performance when used to predict cancer treatment outcomes. This problem is partly due to the overlooking of functional implications of molecular markers. Here, we present a novel(More)
Demo of Algorithms & Clinical Visualization In 2014, there will be 18,860 new cases of acute myeloid leukemia (AML), and 10,460 deaths from AML. There is urgency in finding better treatments for this type of leukemia, as only about a quarter of the patients diagnosed with AML survive beyond 5 years. The goal of the 2014 DREAM 9 Acute Myeloid Leukemia (AML)(More)
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