Burghard Cordes

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Type II diabetes is characterized by deposition of the hormone human Islet Amyloid Polypeptide (hIAPP). Formation of hIAPP amyloid fibrils and aggregates is considered to be responsible for pancreatic β-cell losses. Therefore, insight into the structure of hIAPP in the solid-state and in solution is of fundamental importance in order to better understand(More)
For the first time, methyltrioxorhenium (MTO) has been applied as a catalyst for the dihydroxylation of allenes in the presence of hydrogen peroxide as the oxidant. The regioselectivities turn out to be well controlled, affording β-carbonyl-γ-hydroxyl diphenyl phosphine oxides as the only product. The axial chirality of optically active allenes can also be(More)
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