Bulent Satar

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OBJECTIVE To determine the hearing outcome in patients undergoing surgery via the retrosigmoid approach for acoustic neuromas with a substantial component in the cerebellopontine angle. STUDY DESIGN Retrospective case review. SETTING Tertiary referral center. PATIENTS The medical records of all patients undergoing acoustic neuroma removal via the(More)
Reactive oxygen species (ROS) have been implicated in hearing loss associated with aging and noise exposure. Superoxide dismutases (SODs) form a first line of defense against damage mediated by the superoxide anion, the most common ROS. Absence of Cu/Zn SOD (SOD1) has been shown to potentiate hearing loss related to noise exposure and age. Conversely,(More)
The Kresge Hearing Research Institute-3 (KHRI-3) antibody binds to a guinea pig inner ear supporting cell antigen (IESCA) and causes hearing loss. To gain insight into the mechanism of antibody-induced hearing loss, we used antibody immunoaffinity purification to isolate the IESCA, which was then sequenced by mass spectroscopy, revealing 10 guinea pig(More)
OBJECTIVE To describe the underrecognized inner ear malformation characterized by complete aplasia of the labyrinthine semicircular canals associated with a relatively well-formed cochlea, to investigate its relationship with known syndromic forms of hearing loss, and to hypothesize regarding the potential embryopathogenesis of this anomaly. STUDY DESIGN(More)
OBJECTIVE The object of this study was to compare the expression of epidermal growth factor, interleukin-1alpha, and tumor necrosis factor-alpha in chronic otitis media with or without cholesteatoma. BACKGROUND It has been reported that cytokines and epidermal growth factor are effective in the bone resorption process in chronic otitis media. Bone(More)
Aim of the study was to investigate whether postoperative middle and late latency responses (MLR and LLR) give some clues of postoperative performance of cochlear implant (CI) users. The study was performed in ten prelingual and six postlingual-CI patients with the age ranging from 6 to 48 years (mean 19.7 +/- 15.7 years). The following criteria were sought(More)
OBJECTIVE To document immunologic findings in patients with recurrent facial paralysis (RFP) and to compare the results of the surgery with the results of medical treatment. STUDY DESIGN Retrospective case review. SETTING Tertiary care referral center. PATIENTS Nine patients with RFP were reviewed. INTERVENTION Patients underwent nonspecific(More)
We aimed to investigate if there is a concordance between summation potential (SP)/action potential (AP) ratio and unilateral weakness in patients with definite-Meniere's disease. There were two groups, a group of unilateral definite-Meniere patients who received no treatment and another group of control subjects. Twenty-six patients were identified as(More)
HYPOTHESIS To investigate effects of dexamethasone and hyperbaric oxygen therapy (HBOT) on proinflammatory cytokines and hearing levels in the noise-exposed cochlea of rats. BACKGROUND There is an arising concern about negative effects of early initiation of HBOT on hearing in noise-induced hearing loss. Furthermore, effects of HBOT and dexamethasone on(More)