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Studies were performed on isolated perfused kidneys (IPK) from postnatal developing rabbits to ask 1) whether the high renal vascular resistance (RVR) at birth involves intrinsic renal mechanisms, 2)… (More)
Background: To examine the postnatal development of AngII vasoconstictory effect and the role of AT1 and AT2 receptors in the in vitro, rabbit isolated perfused kidney (IPK).
Neonatal renal hemodynamics are characterized by a specific pattern of reactivity to various mediators, including nitric oxide (NO). Knowlegde on the role of NO in renal hemodynamics often relies on… (More)
AII is involved in the control of neonatal renal hemodynamics and has been shown to interact with nitric oxide (NO) according to a specific developmental pattern. Distribution of AII receptor AT1 and… (More)