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In vivo implants of demineralized dentin matrix into muscle induce the formation of bone within the muscle. As with bone matrix implants, the bone induction appears to follow a chondrogenic pathway. Outgrowth cells from explants of neonatal rat muscle respond to bone matrix, in vitro, by expressing a heightened synthesis of sulfated proteoglycans and type(More)
BACKGROUND Fluid resuscitation remains a fundamental component of early burn care management. However, recent studies suggest that excessive volumes of resuscitation are being administered. Overresuscitation results in negative sequelae including abdominal and extremity compartment syndromes. Elevated intraocular pressure (IOP) has been described as another(More)
OBJECTIVE To measure any sex size differences in the bony nasolacrimal drainage systems in a normal, age-matched population. METHODS A retrospective study of axial cut maxillofacial computed tomographic scans was conducted. Three levels of the bony nasolacrimal duct (NLD) system on the right and left sides were measured along the anteroposterior diameter.(More)
Demineralized dentin matrix has the capacity to induce bone formation via a chondrogenic pathway when implanted into muscle, in a fashion entirely analogous to bone matrix implants. In this work we have attempted to isolate, from rat incisor dentin, the matrix factor responsible for initiating osteogenesis. Rat incisor dentin was demineralized with EDTA(More)
PURPOSE To identify clinical characteristics of burn patients requiring emergent orbital decompression for vision-threatening orbital compartment syndrome. METHODS A retrospective review of 28 burn patients at a trauma center provided data regarding demographics, physical examination findings, and resuscitation fluid volumes. Patients requiring orbital(More)
Radiesse is a filler material for deep nasolabial folds that was recently approved by the United States Food and Drug Administration. It is composed of calcium hydroxylapatite crystals measuring 25 mum to 45 mum. Few complications have been reported to date. We present a case of a woman who developed herpetic appearing skin lesions after the injection of(More)
PURPOSE To observe the effect of mitomycin C (MMC) on cultured human nasal mucosa fibroblasts. METHODS Cultured human nasal mucosa fibroblasts were exposed to MMC (0.1-0.4 mg/ml) for 1 to 5 minutes. The viability of the fibroblasts was determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) assay; DNA fragmentation (apoptosis) by(More)