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  • Blaine N. Armbruster, Xiang Li, Mark H. Pausch, Stefan Herlitze, Bryan L. Roth
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2007 (First Publication: 20 March 2007)
  • We evolved muscarinic receptors in yeast to generate a family of G protein-coupled receptors (GPCRs) that are activated solely by a pharmacologically inert drug-like and bioavailable compoundExpand
  • Bryan L. Roth
  • Biology, Medicine
  • Neuron
  • 2016 (First Publication: 17 February 2016)
  • To understand brain function, it is essential that we discover how cellular signaling specifies normal and pathological brain function. In this regard, chemogenetic technologies represent valuableExpand