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OBJECTIVES To observe the effects of etanercept treatment on the cutaneous manifestations of hidradenitis suppurative (HS) and to evaluate physician and patient global assessment scores of cutaneous manifestations. DESIGN Single-center, randomized, prospective, double-blind, placebo-controlled study. SETTING Academic dermatology practice. PATIENTS(More)
BACKGROUND Allergic contact dermatitis from nickel is very common in the United States. A barrier coating to be used on personal items such as snaps or watches would be of great use in preventing the consequences of nickel allergy. OBJECTIVE To evaluate various barrier coatings and their ability to yield a negative dimethylglyoxime (DMG) test result. (More)
OBJECTIVE Tolerability and safety of 0.1% tacrolimus ointment in treating nickel-induced allergic contact dermatitis (ACD) were evaluated. METHODS Patients allergic to nickel applied nickel patches to each upper inner aspect of the arm for 4 to 8 hours daily. Tacrolimus was applied to patch site on one arm and vehicle to patch site on the other, twice(More)
BACKGROUND Lidocaine hydrochloride is the preferred anesthetic agent used in outpatient surgical procedures. While type I hypersensitivity reactions to lidocaine are uncommon, type IV hypersensitivity is reported even less frequently. OBSERVATIONS Between January 1, 2001, and December 31, 2001, 183 patients were patch tested at the Penn State Milton S.(More)
BACKGROUND Alopecia mucinosa has been shown to be associated with many benign and malignant conditions. It can be seen in childhood but is seen more commonly in adulthood. Alopecia mucinosa is generally felt to occur in three settings: a primary idiopathic form, a form associated with malignancy, and a form secondary to inflammatory conditions. The(More)
Human ehrlichiosis is a zoonotic disease, caused by a rickettsia that infects leukocytes. It was described for the first time in the United States of America in 1986. More than 300 cases have been reported in that country. One case has been reported in Portugal, two in France and one more in a tourist coming from Mali (Africa). In Venezuela, a tropical(More)
Eczema herpeticum is a potentially life-threatening herpetic superinfection of a pre-existing skin disease. Despite the availability of antiviral therapies, eczema herpeticum remains a dermatologic emergency today. Two representative cases of eczema herpeticum along with discussion of the etiology, means of diagnosis, treatments, and complications of eczema(More)