Brunhilde Kissig

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An epidemiological study of multiple sclerosis (MS) in the district of Halle, Halle-Neustadt and the area near the river Saale was carried out. We found 178 patients with a definite diagnosis in a total population of 396,529, corresponding to a prevalence of 44.9/100,000. The annual incidence rate was 2/100,000. When probable but not definitely diagnosed(More)
The diagnostic value of CSF oligoclonal IgG bands, intrathecal IgG synthesis, cytology and markers of myelin breakdown in the cerebro-spinal fluid were evaluated in multiple sclerosis. None of the various immunological alterations were unique to MS. The diagnosis depends therefore mainly on course and clinical symptoms, but can be supported by CSF analysis.
We report on the clinical symptomatology, diagnostic difficulty and inadequate possibilities for treatment of 6 patients suffering from primary agiitis of intracranial vessels. They died at age 36 to 64 years. The duration of the disease varied between 6 weeks and 11 1/2 years and was diagnosed, autoptically in all cases, as giant cell angiitis (2 cases)(More)
There are neither specific cell investigations nor immunological tests for the diagnosis of MS. Various immunological alterations occur in the course of the disease, but none is unique to MS. Accurate diagnosis remains confined to the clinical field. The diagnosis can be supported by CSF analysis. Laboratory examinations can help to determine the particular(More)
  • R Lahl, B Kissig
  • 1984
It is reported on the clinical and morphological findings of two women with obliterating thrombendangiitis who finally died of the sequelae of this vascular disease at the age of 36 years and 64 years, respectively, after a 14-year and 10-month duration of the disease. Despite generalisation or multilocalisation of the disease only the cerebral(More)