Selective interaction of a conformationally-constrained Arg-Gly-Asp (RGD) motif with the integrin receptor alphavbeta3 expressed on human tumor cells.
- P. Lanza, B. Felding-Habermann, Z. Ruggeri, M. Zanetti, R. Billetta
- Blood cells, molecules & diseases
Two antigenized antibodies (AgAbs) were engineered to express peptidic Arg-Gly-Asp (RGD) motifs present in extracellular matrix molecules. The RGD tripeptide sequence was inserted in the third… Expand
Tumor cell-platelet interaction in metastatic disease.
- B. Felding-Habermann