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In order to assess the presence of tuberculosis in Pleistocene bison and the origin of tuberculosis in North America, 2 separate DNA extractions were performed by 2 separate laboratories on samples from the metacarpal of an extinct long-horned bison that was radiocarbon dated at 17,870+/-230 years before present and that had pathological changes suggestive(More)
OBJECTIVE To determine the relationship of what has been called pre-Columbian Old World rheumatoid arthritis (RA) to the RA identified in pre-Columbian North America. METHODS All published claims of pre-Columbian Old World RA were reviewed against the established North American standard for its recognition in archeologic sites. Those characteristics(More)
Rheumatoid arthritis was first described unambiguously in 1800, but its etiology and historical origins are still obscure. Definite rheumatoid arthritis has not been demonstrated in pre-19th century Old World skeletal remains. Six individuals who lived 3000 to 5000 years ago in northwestern Alabama and present erosive polyarthritis characteristic of(More)
Occasional reports in isolated fragments of dinosaur bones have suggested that tumors might represent a population phenomenon. Previous study of humans has demonstrated that vertebral radiology is a powerful diagnostic tool for population screening. The epidemiology of tumors in dinosaurs was here investigated by fluoroscopically screening dinosaur(More)
Documentation of the antiquity and tracking of the derivation of human treponemal diseases have been complicated by an inability to distinguish among these diseases biochemically, histologically, and immunologically. Skeletal impact, as a population phenomenon, has been suspected to vary sufficiently among the treponemal disorders to allow their(More)
Decompression syndrome (caisson disease or the “the bends”) resulting in avascular necrosis has been documented in mosasaurs, sauropterygians, ichthyosaurs, and turtles from the Middle Jurassic to Late Cretaceous, but it was unclear that this disease occurred as far back as the Triassic. We have examined a large Triassic sample of ichthyosaurs and compared(More)
STUDY DESIGN A descriptive study of the association between sacroiliac joint bridging (SIB) and age, gender, laterality, and ethnic origin in a normal skeletal population. The effectiveness of radiographs in identifying SIB was also evaluated. OBJECTIVES To characterize the phenomenon of SIB demographically and anatomically and to evaluate the validity of(More)
Systematic survey of mammalian skeletons has revealed patterns of disease reproducible over geologic time. Systematic examination of non-passerine bird skeletons also reveals patterns of disease and identifies those disorders amenable to epidemiologic assessment. Neoplasia, infection, osteochondromatosis and gout are extremely rare, precluding phylogenetic(More)