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  • P. Andrade-Gordon, B. Maryanoff, +12 authors K. B. White
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Publication: 26 October 1999)
  • Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus thatExpand
  • Claudia K. Derian, Bruce P. Damiano, +6 authors Patricia Andrade-Gordon
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2003 (First Publication: 1 February 2003)
  • Although it is well recognized that human platelet responses to α-thrombin are mediated by the protease-activated receptors PAR-1 and PAR-4, their role and relative importance in platelet-dependentExpand
  • Bruce E Maryanoff, Rosemary J. Santulli, +6 authors Patricia Andrade-Gordon
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 2001 (First Publication: 1 February 2001)
  • Protease-activated receptor-2 (PAR-2) is a tethered-ligand, G-protein-coupled receptor that is activated by proteolytic cleavage or by small peptides derived from its cleaved N-terminal sequence,Expand
  • Patricia Andrade-Gordon, Claudia K. Derian, +11 authors D. F. Mccomsey
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 2001 (First Publication: 1 July 2001)
  • Human platelets possess two distinct thrombin-activated receptors, PAR-1 (protease-activated receptor-1) and PAR-4, whereas human vascular smooth muscle cells possess only PAR-1. Although suchExpand