Bruce Barton

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The Silent Cerebral Infarct Multicenter Transfusion (SIT) Trial is a multi-institutional intervention trial in which children with silent cerebral infarcts are randomized to receive either blood transfusion therapy or observation (standard care) for 36 months. The SIT Trial is scheduled to enroll approximately 1,880 children with sickle cell disease from 29(More)
(2016). Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion. Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. Developmental trajectories of young children with neurofibromatosis type 1: a(More)
(2016). Uptake of health monitoring and disease self-management in Australian adults with neurofibromatosis type 1: strategies to improve care. Developmental trajectories of young children with neurofibromatosis type 1: a longitudinal study from 21 to 40 months of age. (2015). Online parent-targeted cognitive-behavioural therapy intervention to improve(More)
BACKGROUND Dantrolene is neuroprotective in animal models and may attenuate cerebral vasospasm (cVSP) in human aneurysmal subarachnoid haemorrhage (aSAH). We evaluated safety, feasibility and tolerability of intravenous dantrolene (IV-D) in patients with aSAH. METHODS In this single-centre, randomised, double blind, placebo-controlled trial, 31 patients(More)
OBJECTIVES The goal of this project was to develop the first disease-specific instrument for the evaluation of quality of life in chronic pancreatitis. METHODS Focus groups and interview sessions were conducted, with chronic pancreatitis patients, to identify items felt to impact quality of life which were subsequently formatted into a paper-and-pencil(More)
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