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PURPOSE Depression is common in primary care. There are no systematic reviews of depression treatment comparing antidepressants with placebo; hence, we do not know whether these medications are effective in primary care. METHODS We searched the Cochrane Collaboration Depression, Anxiety and Neurosis Group register of controlled trials, MEDLINE,(More)
OBJECTIVE To assess the long term effectiveness of the "green prescription" programme, a clinician based initiative in general practice that provides counselling on physical activity. DESIGN Cluster randomised controlled trial. Practices were randomised before systematic screening and recruitment of patients. SETTING 42 rural and urban general practices(More)
PURPOSE We wanted to assess the effectiveness of a home-based physical activity program, the Depression in Late Life Intervention Trial of Exercise (DeLLITE), in improving function, quality of life, and mood in older people with depressive symptoms. METHODS We undertook a randomized controlled trial involving 193 people aged 75 years and older with(More)
PURPOSE Although screening for unipolar depression is controversial, it is potentially an efficient way to find undetected cases and improve diagnostic acumen. Using a reference standard, we aimed to validate the 2- and 9-question Patient Health Questionnaires (PHQ-2 and PHQ-9) in primary care settings. The PHQ-2 comprises the first 2 questions of the(More)
OBJECTIVE To determine the diagnostic accuracy of two verbally asked questions for screening for depression. DESIGN Cross sectional criterion standard validation study. SETTING 15 general practices in New Zealand. PARTICIPANTS 421 consecutive patients not taking psychotropic drugs. MAIN OUTCOME MEASURES Sensitivity, specificity, and likelihood(More)
AIM To assess the prevalence and severity of acne vulgaris in adolescent students. METHOD 867 students in Auckland sixth and seventh form classes were interviewed on the subject of acne vulgaris. Of these 847 students were examined and graded for severity of their acne using a modification of the Leeds technique which ranks severity according to number,(More)
OBJECTIVE To evaluate whether provision of fixed dose combination treatment improves adherence and risk factor control compared with usual care of patients at high risk of cardiovascular disease in primary care. DESIGN Open label randomised control trial: IMPACT (IMProving Adherence using Combination Therapy). SETTING 54 general practices in the(More)
OBJECTIVES The purpose of this study was to determine whether written advice from general practitioners increases physical activity among sedentary people more than verbal advice alone. METHODS Sedentary patients (n = 456) received verbal advice on increasing physical activity and were then randomized to an exercise prescription (green prescription) group(More)
BACKGROUND It has long been believed that antibiotics have no role in treating common colds yet they are often prescribed in the belief that they may prevent secondary bacterial infections. Given the increasing concerns about antibiotic resistance it is important to examine the evidence for the benefit of antibiotics for the common cold. OBJECTIVES To(More)