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PURPOSE Depression is common in primary care. There are no systematic reviews of depression treatment comparing antidepressants with placebo; hence, we do not know whether these medications are effective in primary care. METHODS We searched the Cochrane Collaboration Depression, Anxiety and Neurosis Group register of controlled trials, MEDLINE,(More)
BACKGROUND Depression is common in primary care and clinicians are encouraged to screen their patients. Meta-analyses have evaluated the effectiveness of screening, but two author groups consistently reached completely opposite conclusions. METHODS We identified five systematic reviews on depression screening conducted between 2001 and 2009, three by(More)
OBJECTIVE To assess the effectiveness of an activity programme in improving function, quality of life, and falls in older people in residential care. DESIGN Cluster randomised controlled trial with one year follow-up. SETTING 41 low level dependency residential care homes in New Zealand. PARTICIPANTS 682 people aged 65 years or over. INTERVENTIONS(More)
INTRODUCTION Venous ulcers are usually treated with compression therapy, but, because this treatment may not be effective for some people, adjuvant therapy could be beneficial. We did a systematic review of randomised controlled trials that compared pentoxifylline (with and without compression treatment) with placebo, or other treatments, in patients with(More)
BACKGROUND Physical activity shows potential in combating the poor outcomes associated with depression in older people. Meta-analyses show gaps in the research with poor trial design compromising certainty in conclusions and few programmes showing sustained effects. METHODS/DESIGN The Depression in Late Life: an Intervention Trial of Exercise (DeLLITE) is(More)
BACKGROUND Insufficient data exist on population-based trends in morbidity and mortality to determine the success of prevention strategies and improvements in health care delivery in stroke. The aim of this study was to determine trends in incidence and outcome (1-year mortality, 28-day case-fatality) in relation to management and risk factors for stroke in(More)
OBJECTIVE To determine the diagnostic accuracy of the two questions with help question (TQWHQ) in the Malay language. The two questions are case-finding questions on depression, and a question on whether help is needed was added to increase the specificity of the two questions. METHOD This cross sectional validation study was conducted in a government(More)
INTRODUCTION Māori are disproportionately affected by cardiovascular disease (CVD), which is the main reason for the eight year difference in life expectancy between Māori and non-Māori. The primary care-based IMPACT (IMProving Adherence using Combination Therapy) trial evaluates whether fixed dose combination therapy (a "polypill") improves adherence to(More)
AIM To assess nutrition curriculum guidelines for undergraduate medical education in the United States, Canada, the United Kingdom, Republic of Ireland, Australia, and New Zealand to highlight potential opportunities for shared learning on the advancement of nutrition in medical education. METHODS A comprehensive list of professional bodies, councils,(More)