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PURPOSE Although screening for unipolar depression is controversial, it is potentially an efficient way to find undetected cases and improve diagnostic acumen. Using a reference standard, we aimed to validate the 2- and 9-question Patient Health Questionnaires (PHQ-2 and PHQ-9) in primary care settings. The PHQ-2 comprises the first 2 questions of the(More)
OBJECTIVE To assess the long term effectiveness of the "green prescription" programme, a clinician based initiative in general practice that provides counselling on physical activity. DESIGN Cluster randomised controlled trial. Practices were randomised before systematic screening and recruitment of patients. SETTING 42 rural and urban general practices(More)
OBJECTIVE To determine the diagnostic accuracy of two verbally asked questions for screening for depression. DESIGN Cross sectional criterion standard validation study. SETTING 15 general practices in New Zealand. PARTICIPANTS 421 consecutive patients not taking psychotropic drugs. MAIN OUTCOME MEASURES Sensitivity, specificity, and likelihood(More)
PURPOSE Depression is common in primary care. There are no systematic reviews of depression treatment comparing antidepressants with placebo; hence, we do not know whether these medications are effective in primary care. METHODS We searched the Cochrane Collaboration Depression, Anxiety and Neurosis Group register of controlled trials, MEDLINE,(More)
BACKGROUND Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication. There is a need to review the evidence of only those studies that have been conducted comparing antidepressant efficacy with placebo in primary care-based samples. OBJECTIVES To(More)
AIM To assess the cost-effectiveness of the 'Green Prescription' physical activity counselling programme in general practice. METHOD Prospective cost-effectiveness study undertaken as part of a cluster randomised controlled trial with 12-month follow-up of 878 'less-active' patients aged 40-79 years in 42 general practices in the Waikato. The intervention(More)
OBJECTIVE To determine the validity of two written screening questions for depression with the addition of a question inquiring if help is needed. DESIGN Cross sectional validation study. SETTING 19 general practitioners in six clinics in New Zealand. PARTICIPANTS 1025 consecutive patients receiving no psychotropic drugs. MAIN OUTCOME MEASURES(More)
BACKGROUND To determine the accuracy of transvaginal ultrasonography, sonohysterography and diagnostic hysteroscopy for the investigation of abnormal uterine bleeding in premenopausal women. DESIGN Systematic review of common diagnostic imaging tests. DATA SOURCES Relevant papers were identified through electronic searching of MEDLINE (1980 to July(More)
PURPOSE We wanted to assess the effectiveness of a home-based physical activity program, the Depression in Late Life Intervention Trial of Exercise (DeLLITE), in improving function, quality of life, and mood in older people with depressive symptoms. METHODS We undertook a randomized controlled trial involving 193 people aged 75 years and older with(More)
OBJECTIVE To compare the efficacy and tolerability of tricyclic antidepressants with selective serotonin reuptake inhibitors in depression in primary care. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Register of the Cochrane Collaboration's depression, anxiety, and neurosis group. Reference lists of initial(More)