Brock A. Wester

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— Existing brain-computer interface (BCI) control of highly dexterous robotic manipulators and prosthetic devices typically rely solely on neural decode algorithms to determine the user's intended motion. Although these approaches have made significant progress in the ability to control high degree of freedom (DOF) manipulators, the ability to perform(More)
Intracranial electroencephalographic (iEEG) signals from two human subjects were used to achieve simultaneous neural control of reaching and grasping movements with the Johns Hopkins University Applied Physics Lab (JHU/APL) Modular Prosthetic Limb (MPL), a dexterous robotic prosthetic arm. We performed functional mapping of high gamma activity while the(More)
OBJECTIVE We used native sensorimotor representations of fingers in a brain-machine interface (BMI) to achieve immediate online control of individual prosthetic fingers. APPROACH Using high gamma responses recorded with a high-density electrocorticography (ECoG) array, we rapidly mapped the functional anatomy of cued finger movements. We used these(More)
Mechanisms of primary blast injury caused by overpressure are not fully understood. In particular, the presence and time course of neuroinflammation are unknown and so are the signatures of reactive inflammatory cells, especially the neuroprotective versus injurious roles of microglia. In general, chronic microglial activation in the injured brain suggests(More)
OBJECTIVE One approach to conveying sensory feedback in neuroprostheses is to electrically stimulate sensory neurons in the cortex. For this approach to be viable, it is critical that intracortical microstimulation (ICMS) causes minimal damage to the brain. Here, we investigate the effects of chronic ICMS on the neuronal tissue across a variety of(More)
— This paper presents the experimental validation of software-based safety features implemented during the control of a prosthetic limb in self-feeding tasks with a human patient. To ensure safe operation during patient controlled movements of the limb, velocity-based virtual fixtures are constructed with respect to the patient's location and orientation(More)
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