Brittany J. Lee

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SUMMARY Karyopherinb (Kapb) proteins bind nuclear lo-calization and export signals (NLSs and NESs) to mediate nucleocytoplasmic trafficking, a process regulated by Ran GTPase through its nucleotide cycle. Diversity and complexity of signals recognized by Kapbs have prevented prediction of new Kapb substrates. The structure of Kapb2 (also known as(More)
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