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Clinico-pathological characteristics of different types of immunodeficiency-associated smooth muscle tumours.
In all three tumour subtypes, survival analyses did not show any significant differences regarding surgical therapeutic approaches, the occurrence of multiple tumours, tumour size or sarcoma-like histological features. Expand
Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension.
A novel molecular mechanism of oxidative stress stimulated covalent EGFR dimerization via tyrosine Dimerization that contributes into development of PH is provided. Expand
Nitration of Tyrosine 247 Inhibits Protein Kinase G-1α Activity by Attenuating Cyclic Guanosine Monophosphate Binding*
The study shows that the nitration of Tyr247 and the attenuation of cGMP binding is an important mechanism regulating in PKG-1α activity and SMC proliferation/differentiation. Expand
Tumour angiogenesis in Epstein-Barr virus-associated post-transplant smooth muscle tumours
Tumour angiogenesis in PTSMT is characterised by low levels of major pro-angiogenic factors and there is no prominent increase in tumour vascularisation, which could be an explanation why, despite EBV infection, PTSMT show no exaggerated tumourAngiogenesis. Expand