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A set of 17 voices representing various voice disorders were presented to a jury of voice experts who rated them on a 5-point scale for each of 28 terms frequently used for describing voices. A statistical treatment of these ratings yielded 5 bipolar factors accounting for 85% of the total variance. Significant correlations were found between four of these(More)
With current progress in genetic research, autosomal, dominant, hereditary, neurodegenerative diseases, affecting the cerebellum and cerebellar connections, are increasingly diagnosed as spinocerebellar ataxias (SCA). In the present study speech samples from 21 subjects with spinocerebellar ataxia (SCA), and 21 matched control subjects were analyzed using(More)
OBJECTIVES To evaluate a new analysis system, High-Speed Tool Box (H. Larsson, custom-made program for image analysis, version 1.1, Department of Logopedics and Phoniatrics, Huddinge University Hospital, Huddinge, Sweden, 1998) for studying vocal fold vibrations using a high-speed camera and to relate findings from these analyses to sound characteristics.(More)
A dual affinity fusion concept has been developed in which the gene encoding the desired product is fused between two flanking heterologous genes encoding IgG- and albumin-binding domains. Using sequential IgG and serum albumin affinity chromatography, a full-length tripartite fusion protein is obtained. This approach was used to recover a full-length(More)
Preschool teachers are at risk for developing voice problems such as vocal fatigue and vocal nodules. The purpose of this report was to study preschool teachers' voice use during work. Ten healthy female preschool teachers working at daycare centers (DCC) served as subjects. A binaural recording technique was used. Two microphones were placed on both sides(More)
The performance of seven acoustic measures of cycle-to-cycle variations (perturbations) in the speech waveform was compared. All measures were calculated automatically and applied on running speech. Three of the measures refer to the frequency of occurrence and severity of waveform perturbations in special selected parts of the speech, identified by means(More)
Seventeen healthy women, 45 to 61 years old, were examined using videofiberstroboscopy during phonation at three loudness levels. Two phoniatricians evaluated glottal closure using category and ratio scales. Transglottal airflow was studied by inverse filtering of the oral airflow signal recorded in a flow mask (Glottal Enterprises System) during the spoken(More)
A voice accumulator is a portable device for long-term measurements of voice use in natural conditions. A contact microphone attached to the front part of the neck registers vocal fold vibrations. The purposes of the present study were: 1) to evaluate the voice accumulator's two measuring programs optimized for registration of fundamental frequency (F0) and(More)
In an investigation of the speech of layngedomized speakers we presently focus on their ability to distinguish behoeen voiced and voiceless speech sounds. Some of them are able to produce this distinction clearly in some contexts and it is quite remarkable considering the structure of the pharyngo-esophageal entrance, serving as the post-operative voice(More)
AIMS To investigate the Voice Handicap Index (VHI), the health-related quality of life (HRQL), and the correlations between VHI and HRQL in laryngectomees. METHODS Forty-three laryngectomized persons participated (mean age 68;6 years, time since laryngectomy between 0;6 and 12 years). Evaluation of voice handicap was done with the VHI. HRQL was evaluated(More)