Bridget Khursheed

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Signalling by steroid hormones is mediated by receptor proteins that bind hormonal ligands and regulate the transcription of specific genes. The heat-shock protein hsp90 seems to associate selectively with unliganded receptors (aporeceptors), but it has not been determined whether this interaction affects receptor function in vivo. To address the role of(More)
We have cloned and sequenced two barley alpha-amylase genes belonging to the high pI isozyme family, one of which, Amy6-4, corresponds to a cDNA previously characterized by our laboratory. A 750-base pair probe from Amy6-4, representing primarily the promoter/upstream sequences cross-hybridizes on genomic Southern blots under stringent conditions to five(More)
Site-specific mutagenesis of the highly conserved milk box (-140 to -110) region suggested that beta-casein expression is regulated by a hormone-mediated relief of repression (M. Schmitt-Ney, W. Doppler, R. K. Ball, and B. Groner, Mol. Cell. Biol. 11:3745-3755, 1991). However, when this sequence was placed upstream of a heterologous thymidine kinase(More)
This paper looks at the concept of invisible learning in the context of the Oxford University Enabling Mothers to Understand Maternity (E-Mum) project. It argues that users take in messages from an online system’s structure, layout and navigation alongside more direct methods of information uptake such as reading or scanning. If this subliminal absorption(More)
Plant genes usually have multiple potential poly(A) addition signals, and different sites are used for 3' processing of transcripts from a single gene. In contrast, we show here that four barley genes that also have multiple poly(A) addition signals conforming to the plant consensus use only one signal. In each of these genes, the region of cleavage for(More)
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