Bridget B. Kelly

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Cardiovascular disease is the leading cause of death worldwide, affecting not only high-income but also low- and middle-income countries. Nearly 80 percent of all estimated cardiovascular disease-related deaths worldwide now occur in low- and middle-income countries, where nearly 30 percent of all deaths are attributable to cardiovascular disease. The(More)
Cardiovascular disease (CVD) is the leading cause of mortality worldwide, with more than 80% of CVD deaths occurring in low- and middle-income countries (LMICs). There have been several calls for action to address the global burden of CVD, but there remains insufficient investment in and implementation of CVD prevention and disease management efforts in(More)
Cardiovascular disease (CVD) and related chronic diseases are now recognized as the leading causes of death worldwide, with 80% of all CVD-related deaths now occurring in lowand middle-income countries (LMICs).1 Cardiovascular disease risk factors have also increased globally. In addition to the disease burden, global CVD imposes a substantial economic(More)
With the September 2011 United Nations High Level Meeting on Noncommunicable Diseases, the world’s attention is turning to the critically important issue of chronic diseases. The global community is on the threshold of what could be a major change leading to progress in the control of chronic diseases worldwide – progress that could be achieved as a(More)
Cardiovascular disease (CVD) is often thought to be a problem of wealthy, industrialized nations. In fact, as the leading cause of death worldwide, CVD now has a major impact not only on developed nations but also on low and middle income countries, where it accounts for nearly 30% of all deaths. The increased prevalence of risk factors for CVD and related(More)
The dystrophin glycoprotein complex (DGC) is critical for muscle stability, and mutations in DGC proteins lead to muscular dystrophy. The DGC also contributes to the maturation and maintenance of the neuromuscular junction (NMJ). The gene encoding the DGC protein alpha-dystrobrevin undergoes alternative splicing to produce at least five known isoforms.(More)
Previous investments in public health research and education played major roles in improving population health and increasing life expectancy [1,2]. In the early 1900s, amidst efforts to eliminate hookworm from the southern United States (US), Welch and Flexner recognized the need to train public health leaders. They proposed a freestanding public health(More)