Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
DJ-1 is a redox-sensitive protein with several putative functions important in mitochondrial physiology, protein transcription, proteasome regulation, and chaperone activity. High levels of DJ-1… Continue Reading
Parkinson's disease (PD) is a complex, chronic and progressive neurodegenerative disease. While the etiology of PD is likely multifactorial, the protein α-synuclein is a central component to the… Continue Reading
α-Synuclein plays a central role in the pathogenesis of Parkinson's disease (PD); interventions that decrease its expression appear neuroprotective in PD models. Successful translation of these… Continue Reading
LRRK2 has been implicated in endolysosomal function and likely plays a central role in idiopathic Parkinson's disease (iPD). In iPD, dopaminergic neurons within the substantia nigra are characterized… Continue Reading
Evidence of decreased mitochondrial complex I activity within the brain and peripheral tissues of idiopathic and familial forms of Parkinson’s disease (PD) implies an intrinsic vulnerability in the… Continue Reading
Parkinson’s disease (PD) is a common neurodegenerative disease, affecting an estimated 7 million adults worldwide. The defining features of PD are a set of motor deficits that progressively impair… Continue Reading