Brian Stein

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ICD-9-CM diagnosis codes are increasingly used to estimate the burden of disease, as well as to evaluate the quality of care and outcomes of various conditions. Acute exacerbations of COPD (AE-COPD) are common and associated with substantial health and financial burden in the U.S. Whether published algorithms that employ different combinations of ICD-9-CM(More)
AIMS The efficacy of erlotinib (Tarceva, Roche Products, Dee Why, Australia) has been demonstrated in patients with advanced non-small-cell lung cancer (NSCLC). Tarceva lung cancer survival treatment (TRUST) is an open-label, single-arm, phase IV global trial which investigated erlotinib in advanced NSCLC patients who had failed prior therapy or were(More)
BACKGROUND Acute exacerbations of COPD (AE-COPD) are a leading cause of hospitalizations in the United States. To estimate the burden of disease (eg, prevalence and cost), identify opportunities to improve care quality (eg, performance measures), and conduct observational comparative effectiveness research studies, various algorithms based on the(More)
BACKGROUND Little is known about the perception of airflow obstruction in patients hospitalized for acute asthma. OBJECTIVES To evaluate patient perception of airflow obstruction at hospital discharge and at a 2-week follow-up visit and to determine whether symptom control and/or severity of airflow obstruction identified patients at risk for acute asthma(More)
PURPOSE Patients undergoing extraction are at risk for bisphosphonate-related osteonecrosis of the jaws (BRONJ). A C-terminal crosslinking telopeptide (CTX) level lower than 150 pg/mL has been suggested as a predictor of BRONJ risk. The authors aimed to increase the precision of estimates of the risk of BRONJ in osteoporosis after extraction and to assess(More)
A system was developed to efficiently schedule aircraft into congested resources over long ranges and present that schedule as a decision support system. The scheduling system consists of a distributed network of independent schedulers, loosely coupled by sharing capacity information. This loose coupling insulates the schedules from uncertainty in(More)
PURPOSE The practicing dentist must frequently advise on the risks involved with dental extractions in the patient taking an anticoagulant. This study assessed the risk of bleeding in a large heterogeneous cohort of patients on warfarin treated by practitioners in training (dental students and junior staff in a teaching hospital). MATERIALS AND METHODS(More)
This paper investigates the issue of high-rate, underwater acoustic communication and the potential of multi-input multi-output (MIMO) techniques to achieve that end; further, this paper suggests that implementation of such a system would benefit from sonar array processing techniques such as multichannel combining. In order to justify this assertion, this(More)
BACKGROUND Source of infection is an independent predictor of sepsis-related mortality. To date, studies have failed to evaluate differences in septic patients based on the source of infection. METHODS Retrospective study of all patients with sepsis admitted to the ICU of a university hospital within a 12month time period. RESULTS Sepsis due to(More)