Brian P. Dwyer

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Nogo receptor (NgR)-mediated control of axon growth relies on the central nervous system-specific type I transmembrane protein Lingo-1. Interactions between Lingo-1 and NgR, along with a complementary co-receptor, result in neurite and axonal collapse. In addition, the inhibitory role of Lingo-1 is particularly important in regulation of oligodendrocyte(More)
Disclaimer This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information,(More)
Astrocytes and neuronal and oligodendroglial perikarya isolated by the method of Norton and Poduslo (1970) were examined by transmission and scanning electron microscopy and inverted phase contrast microscopy. The viability of the cells, as determined by the eosin exclusion method, was also determined. The three cell fractions showed only slight(More)
Disclaimer This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information,(More)
The National Water, Energy and Carbon Sequestration simulation model (WECSsim) is being developed to address the question, " Where in the current and future U.S. fossil fuel based electricity generation fleet are there opportunities to couple CO 2 storage and extracted water use, and what are the economic and water demand-related impacts of these systems(More)
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