Brian O'Connell

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This work studies the dynamics of a gene expression time series network. The network, which is obtained from the correlation of gene expressions, exhibits global dynamic properties that emerge after a cell state perturbation. The main features of this network appear to be more robust when compared with those obtained with a network obtained from a linear(More)
PURPOSE Abutment screw loosening, especially in the case of cemented single tooth restorations, is a cause of implant restoration failure. This study compared three screws (titanium alloy, gold alloy, and gold-coated) with similar geometry by recording the preload induced when torques of 10, 20, and 35 Ncm were used for fixation. MATERIALS AND METHODS Two(More)
OBJECTIVES To provide information on the susceptibility of Staphylococcus aureus causing skin and soft tissue infections (SSTIs) in France, Ireland and the UK. PATIENTS AND METHODS One thousand three hundred and ninety patients attending their general practitioners for skin infections were recruited. Susceptibility to 11 antimicrobials using CLSI(More)
Linezolid is often the drug of last resort for serious methicillin-resistant Staphylococcus aureus (MRSA) infections. Linezolid resistance is mediated by mutations in 23S rRNA and genes for ribosomal proteins; cfr, encoding phenicol, lincosamide, oxazolidinone, pleuromutilin, and streptogramin A (PhLOPSA) resistance; its homologue cfr(B); or optrA,(More)
Major Golf and Grand Slam Tennis tournaments such as Australian Open, The Masters, Roland Garros, United States Golf Association (USGA), Wimbledon, and United States Tennis Association (USTA) United States (US) Open provide real-time and historical sporting information to immerse a global fan base in the action. Each tournament provides realtime content,(More)
To support complex, rapidly changing, high-volume websites many components contribute to keeping the content current. Monitoring the workflow through all these components is a challenging task. This paper describes a system in which monitoring objects created by the various heterogeneous, distributed components are distributed to any application choosing to(More)
Clonal complex (CC) 398 methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) are associated with carriage and infection among animals and humans but only a single case of CC398 MRSA has been reported in the Republic of Ireland (ROI). The present study investigated the molecular epidemiology of CC398 MRSA (n = 22)(More)