Brian Miles

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Article history: Received 17 January 2006 Received in revised form 10 January 2007 Accepted 29 January 2007 Available online 26 March 2007 As coastal disasters become more frequent and costly, a full assessment of costs becomes more important. This paper aims to identify costs of coastal disasters to human, social, built and natural capital and their(More)
Oncolytic adenoviruses as a treatment for cancer have demonstrated limited clinical activity. Contributing to this may be the relevance of preclinical animal models used to study these agents. Syngeneic mouse tumor models are generally non-permissive for adenoviral replication, whereas human tumor xenograft models exhibit attenuated immune responses to the(More)
Herpes simplex virus (HSV) resistance to acyclovir or foscarnet results from mutations in viral thymidine kinase (TK) and/or DNA polymerase (pol) genes. Replication kinetics and virulence of TK and/or DNA pol clinical mutants were assessed using models of mouse encephalitis and cotton rat genital infection. Replication capacities in Vero cells of a DNA pol(More)
The spatial distribution of shallow landslides in steep forested mountains is strongly controlled by aboveground and belowground biomass, including the distribution of root cohesion. While remote sensing of aboveground canopy properties is relatively advanced, estimating the spatial distribution of root cohesion at the forest landscape scale remains(More)
Annually adjusted inactivated influenza vaccines can prevent infection and limit the spread of seasonal influenza when vaccine strain closely matches circulating strain. For the years when the match is difficult to achieve, a rapid screening of a larger repertoire of vaccines may be required but is difficult to accomplish due to the lack of a convenient(More)
U.S. Army Engineer Waterways Experiment Station (WES) investigators have designed, fabricated, and demonstrated a cone penetrometer sensor for subsurface in situ field screening based on LIBS. The LIBS probe (patent pending) presented here is one of a suite of contaminant and geophysical probes developed by the WES Site Characterization and Analysis(More)
Although non-point source (NPS) pathogen pollution is a leading cause of stream impairment in the United States, the sources of NPS pollution are often difficult to ascertain. While previous studies have employed land use regression methods to develop a greater understanding of the sources and dynamics of microbial NPS pollution, little work has explicitly(More)
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