Brian Martin Murphy

Learn More
Immunoassays represent a core workhorse methodology for many applications ranging from clinical diagnostics to environmental monitoring. In traditional formats such as the enzyme linked immunosorbent assay (ELISA), analytes are measured singly or in small sets. As more biomarkers are identified for disease states, there is a need to develop methods that can(More)
New high-throughput immunoassay methods for rapid point-of-care diagnostic applications represent an unmet need and current focus of numerous innovative methods. We report a new micromosaic competitive immunoassay developed for the analysis of the thyroid hormone thyroxine (T4), inflammation biomarker C-reactive protein (CRP), and the oxidative damage(More)
9 There is wide variation in endemic tuberculosis (TB) levels between countries and we seek to identify 10 possible causes of these differences. In this study we present an epidemiological model of Mycobacterium 11 tuberculosis infection to investigate the effects of host genetics and demographic factors on epidemic TB. 12 We discuss the general framework(More)
  • 1