Rani Jacobs3
Vicki Anderson3
3Rani Jacobs
3Vicki Anderson
2Mark Dela Cruz
2Elizabeth Sinclair
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This study examined developmental timing of brain lesion effects on children's attention skills. The sample of 138 children, 10-16 years at assessment, were grouped based on developmental timing of brain lesion: (1) Congenital; (2) Perinatal; (3) Infancy; (4) Preschool; (5) Middle Childhood; (6) Late Childhood. Children with lesions in infancy or earlier(More)
Child stroke is a major cause of death in children, although limited information exists on neurobehavioral functioning of stroke survivors. Executive function (important for goal-directed behavior) is thought to be vulnerable to early insults such as stroke because of its widespread representation in the immature brain. This study investigated the impact of(More)
Childhood stroke is increasingly recognized as a major cause of childhood morbidity and mortality; however, limited information exists regarding neurobehavioral sequelae. Executive function (EF), important for problem solving, reasoning, social awareness, and adaptive behavior, may be particularly vulnerable to early brain lesions such as stroke, due to its(More)
Efficient and accurate digital reconstruction of neurons from large-scale 3D microscopic images remains a challenge in neuroscience. We propose a new automatic 3D neuron reconstruction algorithm, TReMAP, which utilizes 3D Virtual Finger (a reverse-mapping technique) to detect 3D neuron structures based on tracing results on 2D projection planes. Our fully(More)
  • Stephen W. Waldo, Daniel A. Brenner, James M. McCabe, Mark Dela Cruz, Brian Long, Venkata A. Narla +8 others
  • 2015
OBJECTIVE The endothelium is a key mediator of vascular homeostasis and cardiovascular health. Molecular research on the human endothelium may provide insight into the mechanisms underlying cardiovascular disease. Prior methodology used to isolate human endothelial cells has suffered from poor yields and contamination with other cell types. We thus sought(More)
We report a method to facilitate single cell, image-guided experiments including in vivo electrophysiology and electroporation. Our method combines 3D image data acquisition, visualization and on-line image analysis with precise control of physical probes such as electrophysiology microelectrodes in brain tissue in vivo. Adaptive pipette positioning(More)
  • Stephen W. Waldo, Daniel A. Brenner, James M. McCabe, Mark Dela Cruz, Brian Long, Venkata A. Narla +8 others
  • 2015
Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. Copyright: © 2015 Waldo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source(More)
BACKGROUND Squalor is an epiphenomenon associated with a range of medical and psychiatric conditions. People living in squalor are not well described in the literature, and prior work has indicated that up to 50% do not have a psychiatric diagnosis. Squalor appears to be linked with neuropsychological deficits suggestive of the presence of impaired(More)
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