Learn More
CONTEXT Hospital computerized physician order entry (CPOE) systems are widely regarded as the technical solution to medication ordering errors, the largest identified source of preventable hospital medical error. Published studies report that CPOE reduces medication errors up to 81%. Few researchers, however, have focused on the existence or types of(More)
Reproductive factors are associated with reduced risk of breast cancer, but less is known about whether there is differential protection against subtypes of breast cancer. Assuming reproductive factors act through hormonal mechanisms they should protect predominantly against cancers expressing oestrogen (ER) and progesterone (PR) receptors. We examined the(More)
OBJECTIVE The authors sought to determine whether use of methylphenidate in adults is associated with elevated rates of serious cardiovascular events compared with rates in nonusers. METHOD This was a cohort study of new users of methylphenidate based on administrative data from a five-state Medicaid database and a 14-state commercial insurance database.(More)
OBJECTIVE To explore whether treatment with pioglitazone was associated with risk of incident cancer at the 10 most common sites (prostate, female breast, lung/bronchus, endometrial, colon, non-Hodgkin lymphoma [NHL], pancreas, kidney/renal pelvis, rectal, and melanoma). RESEARCH DESIGN AND METHODS A cohort study of 252,467 patients aged ≥40 years from(More)
  • James H Roberds, Brian L Strom, Fred P Hain, David P Gwaze, Steven E Mckeand, Larry H Lott
  • 2003
In southern pines of the United States, resistance to attack by southern pine beetle, Dendroctonus frontalis Zimmermann, is believed to principally involve flow of oleoresin to beetle attack sites. Both environmental and genetic factors are known to affect the quantity of oleoresin flow in loblolly pine, Pinus taeda L., but little is known about the genetic(More)
OBJECTIVE To construct a clinical prediction model for the early identification of children destined to develop refractory temporal lobe epilepsy (TLE) 2 years after epilepsy onset. METHODS Patients with TLE between 1 and 18 years old seen in the Division of Neurology at Children's Hospital of Philadelphia during 1999 were identified through billing(More)
OBJECTIVE Some preclinical in vivo studies and limited human data suggest a possible increased risk of bladder cancer with pioglitazone therapy. This is an interim report of an ongoing cohort study examining the association between pioglitazone therapy and the risk of bladder cancer in patients with diabetes. RESEARCH DESIGN AND METHODS This study(More)
  • J L Carson, A Duff, R M Poses, J A Berlin, R K Spence, R Trout +2 others
  • 1996
BACKGROUND Guidelines have been offered on haemoglobin thresholds for blood transfusion in surgical patients. However, good evidence is lacking on the haemoglobin concentrations at which the risk of death or serious morbidity begins to rise and at which transfusion is indicated. METHODS A retrospective cohort study was performed in 1958 patients, 18 years(More)
OBJECTIVE The authors compared 1-year mortality rates associated with ziprasidone and olanzapine in real-world use. METHOD The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC) was an open-label, randomized, postmarketing large simple trial that enrolled patients with schizophrenia (N=18,154) in naturalistic practice in 18 countries. The(More)
Three major species of Ips bark beetles (Coleoptera: Scolytidae) in the southeastern United States, 1. avulsus (Eichoff), 1. calligraphus (Germar), and 1. grandicollis (Eichoff), attack all species of pines in their range, sometimes causing significant tree mortality (Thatcher, 1960 USDA Forest Service Occasional paper 180, 25 pp.) Co-incident with(More)