Brian K. Hart

  • Citations Per Year
Learn More
alpha 1-Antitrypsin (alpha 1-AT) deficiency may play a role in arterial aneurysmal disease by allowing increased proteolysis of arterial structural proteins. Alpha 1-AT levels are influenced by variation at the PI (protease inhibitor) locus. PI phenotypes were determined in 173 patients with abdominal aortic aneurysms (77 from Pittsburgh, 96 from London)(More)
The University of Pittsburgh's Computing Services and Systems Development organization is focused on the needs of the faculty and student population, totaling nearly 40,000 users. Computing Services and Systems Development has operated the Help Desk call center 24 hours per day, 7 days per week for nearly two years. Concurrent with the establishment of the(More)
Proteolytic imbalance may play a role in the pathogenesis of abdominal aortic aneurysms (AAA). CLG4B, which encodes the 92-kDa form of type IV collagenase, is a candidate gene for AAA. We genotyped a polymorphic dinucleotide repeat in the 5' flanking region of CLG4B in 94 unrelated Caucasian controls and in 127 unrelated Caucasian AAA cases. Eight alleles(More)
This work examines the performance of a hydrous ferric oxide (HFO) reactive filtration (RF) process with coupled chemically enhanced secondary treatment (RECYCLE) for phosphorus removal from municipal wastewater (HFO-RF-RECYCLE). A 3-month, 0.95-ML/d (0.25-mgd) demonstration of HFO-RF-RECYCLE was performed at a municipal wastewater treatment plant equipped(More)
A restraining device for nonhuman primates was designed which effectively prevented the animal from touching the eyes and thereby transferring a topically applied drug from 1 eye to the other. This permitted use of 1 eye of the same animal as a reliable control for observation of pharmacologic effects. The design permitted self-feeding by the animal. It did(More)
Most protocols used for open-path Fourier transform infrared spectrometry (OP/FT-IR) require that spectra be measured at a resolution of 1 cm(-1) and that the concentrations of the analytes be calculated by classical least squares regression (CLS). These specifications were largely developed for monitoring light molecules with easily resolvable rotational(More)
The University of Pittsburgh offers central software license and delivery services in three key areas: general site license and volume discount programs, licensed software for a distributed faculty desktop computing program, and a licensed software pool for student use in campus computing labs. The site license program covers some 500 software titles from(More)
  • 1