Brian Hudson

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Bringing new medicines to the market depends on the rapid discovery of new and effective drugs, often initiated through the biological testing of many thousands of compounds in high-throughput screening (HTS). Mixing compounds together into pools for screening is one way to accelerate this process and reduce costs. This paper contains both theoretical and(More)
In this paper we discuss the background to this study in the development of the international MSc e-Learning Multimedia and Consultancy. The aims of the study focus on the conditions for achieving communication, interaction and collaboration in open and flexible e-learning environments. We present our theoretical framework that has informed the design of(More)
Quantitative structure-property relationships for predicting the water-octanol partition coefficient, logP(OW), are reported. The models are based on local properties calculated at the standard isodensity surface using semiempirical molecular orbital theory and use descriptors obtained as the areas of the surface found in each bin in a predefined binning(More)
The Schools Malaria Project (http://emalaria.soton.ac.uk/) brings together school students with university researchers in the hunt for a new antimalaria drug. The design challenge being offered to students is to use a distributed drug search and selection system to design potential antimalaria drugs. The system is accessed via a Web interface. This(More)
In Online Social Networks (OSNs), the audience size commanded by an organization or an individual is a critical measure of that entity's popularity. This measure has important economic and/or political implications. Organizations can use information about their audience, such as age, location etc., to tailor their products or their message appropriately.(More)
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