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  • Michael Simons, Brian Herb Annex, +9 authors Nicolas A. F. Chronos
  • Medicine
  • Circulation
  • 2002 (First Publication: 19 February 2002)
  • BACKGROUND Single-bolus intracoronary administration of fibroblast growth factor-2 (FGF2) improved symptoms and myocardial function in a phase I, open-label trial in patients with coronary arteryContinue Reading
  • Sanjay Rajagopalan, Emile R. Iii Mohler, +8 authors Brian Herb Annex
  • Medicine
  • Circulation
  • 2003 (First Publication: 21 October 2003)
  • BACKGROUND "Therapeutic angiogenesis" seeks to improve perfusion by the growth of new blood vessels. The Regional Angiogenesis with Vascular Endothelial growth factor (RAVE) trial is the first majorContinue Reading
  • Stephen M Eppler, Daniel L. Mc Combs, +6 authors Thomas F. Zioncheck
  • Medicine
  • Clinical pharmacology and therapeutics
  • 2002 (First Publication: 1 July 2002)
  • BACKGROUND The Vascular Endothelial Growth Factor (VEGF) in Ischemia for Vascular Angiogenesis (VIVA) trial was a double-blind, placebo-controlled, phase II clinical trial designed to evaluate theContinue Reading
  • Richard E. Waters, Ronald L. Terjung, Kevin Gene Peters, Brian Herb Annex
  • Medicine
  • Journal of applied physiology
  • 2004 (First Publication: 1 August 2004)
  • Peripheral arterial occlusive disease (PAOD) is now recognized as a combination of clinical syndromes that are associated with significant morbidity and mortality. The primary pathophysiology of PAODContinue Reading