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- Christopher D. Saudek, William C. Duckworth, +12 authors Neal A Morgan
- JAMA
- 1996
OBJECTIVE
To determine whether implantable insulin pump (IIP) therapy and multiple daily insulin (MDI) injections could equally attain improved blood glucose control, and to compare the 2 treatments… (More)
- Paolo Manunta, J. Hamilton, Andrzej Rogowski, Brian Hamilton, Joanna Hamlyn
- Hypertension research : official journal of the…
- 2000
Elevated circulating levels of an endogenous ouabain (EO) have been associated with essential hypertension. To investigate structure-activity relationships relevant to blood pressure, we infused… (More)
- Joanna Hamlyn, Robert Ringel, +4 authors Mordecai P. Blaustein
- Nature
- 1982
- Paolo Manunta, Brian Hamilton, Joanna Hamlyn
- Hypertension
- 2001
Elevated levels of an endogenous ouabain circulate in many patients with essential hypertension. However, in contrast to ouabain, digoxin does not induce hypertension. This study investigated the… (More)
- J. Laredo, Brian Hamilton, Joanna Hamlyn
- Endocrinology
- 1994
Ouabain is a specific inhibitor of the sodium pump. This steroid has been found in the mammalian circulation in significant amounts and may be of adrenal origin. Secretion of ouabain from adrenal… (More)
- Sascha Gottlieb, Andrzej Rogowski, Mitchell D. Weinberg, Cathy Krichten, Brian Hamilton, Joanna Hamlyn
- Circulation
- 1992
BACKGROUND
An endogenous digitalis-like compound in mammals has long been postulated, but only recently has a substance indistinguishable from ouabain been identified in human plasma. Because of the… (More)
- J. Laredo, Brian Hamilton, Joanna Hamlyn
- Biochemical and biophysical research…
- 1995
Recent experiments have demonstrated the secretion of a ouabain-like compound from primary cultures of bovine adrenocortical cells (1). To determine the relative contribution of the outer zones of… (More)
- Paolo Manunta, Andrzej Rogowski, Brian Hamilton, Joanna Hamlyn
- Journal of hypertension
- 1994
OBJECTIVES
To determine the steady-state dose-dependence of blood pressure, plasma and tissue ouabain during continuous infusion of ouabain in the rat, and to evaluate the adrenal dependence and… (More)
This paper investigates some fourth-order accurate explicit finite difference schemes for the 2-D wave equation obtained using 13-, 17-, 21-, and 25-point discrete Laplacians. Optimisation is… (More)
- Brian Hamilton, Craig J. Webb, Alan Gray, Stefan Bilbao, Shiv Upadhyay
- 2015
Stencil operations are often a key component when performing acoustics simulations, for which the specific choice of implementation can have a significant effect on both accuracy and computational… (More)