Brian H Chon

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PURPOSE To examine the association between myopia and glaucoma, visual field defects, optic disc structural damage, and IOP in a population with a high prevalence of normal-tension glaucoma (NTG). METHODS Data were included from 13,433 participants in the 2008 to 2011 Korean National Health and Nutrition Examination Survey, a cross-sectional study.(More)
Sesquiterpene lactones have raised considerable interest because of their ability to block the activation of nuclear transcription factor-kappaB (NF-kappaB). NF-kappaB plays an important role in the resistance of cancer cells to the induction of apoptosis by anticancer drugs and tumor necrosis factor-alpha (TNF-alpha). Pharmacological inhibition of(More)
Cell supplementation to the herniated or degenerated intervertebral disc (IVD) is a potential strategy to promote tissue regeneration and slow disc pathology. Human umbilical cord mesenchymal stromal cells (HUCMSCs) – originating from the Wharton’s jelly – remain an attractive candidate for such endeavors with their ability to differentiate into multiple(More)
PURPOSE To quantify the predictive strength of anterior chamber area (ACA), anterior chamber volume (ACV), anterior chamber width (ACW), lens vault (LV), iris thickness (IT), and iris area (IArea) for 2 angle width parameters, trabecular-iris space area (TISA750) and angle opening distance (AOD750) at 750 μm from the scleral spur, in different ethnicities.(More)
IMPORTANCE While medication efficacy is well documented in clinical trials, less is known of medication effectiveness in real-world clinical settings. OBJECTIVE To assess the effectiveness of intraocular pressure (IOP)-lowering medications in patients with open-angle glaucoma. DESIGN, SETTING, AND PARTICIPANTS Prospective, multicenter, interventional cohort(More)
IMPORTANCE Little is known about the necessity of multiple same-day intraocular pressure (IOP) measurements in describing the effect of IOP-lowering surgical procedures, and such evidence could affect surgical trial recruitment and retention of participants. OBJECTIVE To determine whether a single IOP measurement might adequately approximate the mean of(More)
Glaucoma is a severe human eye disease that causes permanent loss of vision. The main cause of glaucoma eye disease is the continuous loss of retinal nerve fiber layers due to the increase in the intra ocular pressure inside the eyes. The function of these retinal nerve fibers is the transformation of recognized object information in the form of signals to(More)
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