Brian Frank

Learn More
Deep venous thrombosis (DVT) complicates 60% of knee and 80% of hip arthroplasties performed without prophylactic therapy. Routine postoperative duplex ultrasound surveillance has been proposed for the detection of venous thrombosis following arthroplasty. In order to determine whether surveillance represents an effective strategy to detect postoperative(More)
A wide variety of monomeric and oligomeric, donor-substituted 1,1,4,4-tetracyanobutadienes (TCBDs) have been synthesized by [2+2] cycloaddition between tetracyanoethylene (TNCE) and donor-substituted alkynes, followed by electrocyclic ring opening of the initially formed cyclobutenes. Reaction yields are often nearly quantitative but can be affected by the(More)
business as companies have begun to realize that the number of mobile devices in the world easily eclipses the units of traditional desktop computers. In the mobile-phone space, in particular, you can pick up books written by the likes of the Nokia User Experience team (Mobile Usability: How Nokia Changed the Face of the Mobile Phone). However, with the(More)
A series of monomeric and oligomeric donor-substituted 1,1,4,4-tetracyanobuta-1,3-dienes (TCBDs) with various topologies have been synthesized by means of thermal [2+2] cycloaddition between tetracyanoethylene (TCNE) and donor-substituted alkynes, followed by retro-electrocyclization. One-electron-reduced and -oxidized stages of the donor-substituted TCBDs(More)
Axially chiral, 3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepine (dinaphthazepine) and 1,1'-binaphthyl-2,2'-disulfonimide (dinaphthosulfonimide) moieties were rigidly connected via N-p-phenylene linkers to photochemically (E)/(Z)-isomerisable 1,2-diethynylethene scaffolds. The chemical stability of the resulting systems was found to be critically related to(More)
Axially chiral, N-arylated 3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepines have been prepared by short synthetic protocols from enantiopure 1,1'-bi(2,2'-naphthol) (BINOL) and anilines. Alkynes substituted with two N-phenyldinaphthazepine donors readily undergo a formal [2+2] cycloaddition, followed by retro-electrocyclization, with tetracyanoethene (TCNE)(More)
Background: Chronic pain caused by lumbar stenosis remains a challenging clinical issue. There is a lack of consensus about the use of acupuncture as a potential treatment for lumbar stenosis. Objective: The aim of this study was to review experience with using acupuncture treatment for decreasing pain symptoms and improving functional mobility and(More)