Brian F Renna

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The purpose of this study was to examine whether exercise training, superimposed on compensated-concentric hypertrophy, could increase myocardial hypoperfusion-reperfusion (H/R) tolerance. Female Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) (age: 4 mo; N = 40) were placed into a sedentary (SED) or exercise training (TRD) group(More)
  • L Ashley Mohara, Walter J Smithwick, Steven R Koch, Joseph R Houser, Scott M Libonati, Hajime Macdonnell +15 others
  • 2005
Background—Cardiac responses to ␤-adrenergic receptor stimulation are depressed with pressure overload–induced cardiac hypertrophy. We investigated whether exercise training could modify ␤-adrenergic receptor responsiveness in a model of spontaneous hypertension by modifying the ␤-adrenergic receptor desensitizing kinase GRK2 and the abundance and(More)
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