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The purpose of the present paper is to develop in further detail the remarks, concerning the relationship of Kan functor extensions to closed structures on functor categories, made in "Enriched functor categories" | 1] §9. It is assumed that the reader is familiar with the basic results of closed category theory, including the representation theorem. Apart(More)
OBJECTIVE To determine the return on investment (ROI) of Highmark Inc.'s employee wellness programs. METHODS Growth curve analyses compared medical claims for participants of wellness programs versus risk-matched nonparticipants for years 2001 to 2005. The difference was used to define savings. ROI was determined by subtracting program costs from savings(More)
This study provides the first prospective evaluation of the course and predictors of children's involvement with fire over a 2-year period in 268 nonpatient and patient children (ages 6-13 yrs). Selected predictor variables obtained at initial (intake) assessment, which included fire-specific and general psychosocial measures, were examined in each sample(More)
Herpes simplex virus amplicon vectors expressing RANTES (HSVrantes) and the T-cell costimulatory ligand B7.1 (HSVB7.1) were studied for their ability to elicit a tumor-specific T-cell response in a murine lymphoma model. HSVB7.1- and HSVrantes-transduced EL4 cells expressed high levels of B7.1 and RANTES as analyzed by flow cytometry and enzyme-linked(More)
  • Brian Day
  • 2005
The evidence supporting the therapeutic value of arthroscopic debridement of the knee is overwhelming. However, there is a need for better-designed clinical trials comparing arthroscopic debridement to established alternative treatments. The most important factor in determining success is proper patient selection, and many who have osteoarthritis of the(More)
We developed a technique for measuring patient limb occlusion pressure (LOP) through a tourniquet cuff that overcomes many limitations of existing LOP measurement techniques. The purpose of the study is to determine whether the LOP measured by the proposed technique is statistically or clinically different from that measured by the gold standard Doppler(More)
Strong promonoidal functors are defined. Left Kan extension (also called " existential quantification ") along a strong promonoidal functor is shown to be a strong monoidal functor. A construction for the free monoidal category on a promonoidal category is provided. A Fourier-like transform of presheaves is defined and shown to take convolution product to(More)
Cellular tRNALys-3 serves as the primer for reverse transcription of human immunodeficiency virus, type 1 (HIV-1). tRNALys-3 interacts directly with HIV-1 reverse transcriptase, is packaged into viral particles and anneals to the primer-binding site (PBS) of the HIV-1 genome to initiate reverse transcription. Therefore, the priming step of reverse(More)