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A series of recombinants between Rous-associated virus type 0 (RAV-0), RAV-1, and a replication-competent avian leukosis virus vector (RCAN) have been tested for disease potential in day-old inoculated K28 chicks. RAV-0 is a benign virus, whereas RAV-1 and RCAN induce lymphoma and a low incidence of a variety of other neoplasms. The results of the(More)
Recombinants of Rous-associated virus-0 and Br21 have been used to localize 5' viral sequences that affect the osteopetrotic potential of avian leukosis viruses. Rous-associated virus-0 is a benign subgroup E virus of endogenous origin that does not cause osteopetrosis. Br21 is a constructed subgroup E virus with high osteopetrotic potential. 5' sequences(More)
Mathematical models of epidemic dynamics offer significant insight into predicting and controlling infectious diseases. The dynamics of a disease model generally follow a susceptible, infected, and recovered (SIR) model, with some standard modifications. In this paper, we extend the work of Munz et.al (2009) on the application of disease dynamics to the(More)
ACKNOWLEDGMENTS At the end of my Ph.D. journey, I find myself in the extremely fortunate position of having many people to thank. First and foremost, I owe much to my fantastic advisors, Rod Grupen and Andy Barto, who have been constant sources of wisdom and advice over the past six years. Rod has shown great trust in allowing me to pursue strange and(More)
Visual cortical simple cells show a strong preference for edges of a particular orientation[Hubel and Wiesel, 1962]. The receptive field of the cortical cell shows adjacent excitatory and inhibitory subfields, which are projections from ON-center and OFF-center LGN cells, respectively[Reid and Alonso, 1995]. Here we present a single cell model using ON and(More)
Simple cells found in primary visual cortex are orientation selective. It has been experimentally found that they acquire this property with time i.e. learning of orientation selectivity takes place. Many computational models have been proposed for the development of orientation selectivity. Most of the models proposed so far are either abstract in nature(More)
Introduction Ever since the establishment of the fossil conifer genus Metasequoia Miki from a Cenozoic deposit in Japan (Miki, 1941) and the subsequent discovery of its living species, M. glyptostroboides Hu et Cheng, in south-central China (Hu & Cheng, 1948), the study of Metasequoia has attracted both neo-and paleobota-nists for the past 70 years (for(More)
We'd like to understand how the brain works but that is, at least immediately, an impossible task. In the standard physics fashion we introduce a simplified model of the smallest workable unit of the big problem and make that the system we'd like to understand, namely the neuron. It is a well established idea in neuroscience that signals between neurons is(More)