Brett Wolfson-Stofko

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Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a glycolytic protein responsible for the conversion of glyceraldehyde 3-phosphate (G3P), inorganic phosphate and nicotinamide adenine dinucleotide (NAD(+)) to 1,3-bisphosphoglycerate (1,3-BPG) and the reduced form of nicotinamide adenine dinucleotide (NADH). Here we report the characterization of GAPDH(More)
There are severe neurological complications that arise from HIV infection, ranging from peripheral sensory neuropathy to cognitive decline and dementia for which no specific treatments are available. The HIV proteins secreted from infected macrophages, gp120 and Tat, are neurotoxic. The goal of this study was to screen, identify and develop neuroprotective(More)
BACKGROUND Drug overdose has emerged as the leading cause of injury-related death in the United States, driven by prescription opioid (PO) misuse, polysubstance use, and use of heroin. To better understand opioid-related overdose risks that may change over time and across populations, there is a need for a more comprehensive assessment of related risk(More)
Cyrus Ahalt Joseph Amon Flavia Andrade Jim Anthony Richard Armenta Shervin Assari Jeremiah Barondess Kirsten Bechtel Leo Beletsky Leo Beletsky Gina Besenyi Tina Bloom Ricky Bluthenthal Keosha Bond Jo Boufford Benjamin Bowser Anthony Braga Lauren Brinkley-Rubinstein Adam Carrico Sara Chaganti David Chapin Chunhuei Chi Phillip Coffin Deborah Cohen Brian Cole(More)
BACKGROUND Though public bathroom drug injection has been documented from the perspective of people who inject drugs, no research has explored the experiences of the business managers who oversee their business bathrooms and respond to drug use. These managers, by default, are first-responders in the event of a drug overdose and thus of intrinsic interest(More)
BACKGROUND Mirroring nationwide trends in a broad range of U.S. populations, an alarming number of Afghanistan/Iraq-era U.S. Military veterans have experienced opioid-related overdoses. A growing body of research has examined the proximal behaviors that can precipitate an overdose; considerably less is known about more distal physiological, psychosocial and(More)
1 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA 2 Translational Neuroscience Center, National Institute of Neurological Diseases and Stroke, National Bldg 10, Room 7C-105, 10 Center Drive, Bethesda, MD 20892, USA 3 Section of Infections of the Nervous System, National Institute of Neurological Diseases and(More)
The following report from the field focuses on the authors' collective efforts to operate an ad hoc safer injection facility (SIF) out of portapotties (portable toilets) in an area of the South Bronx that has consistently experienced some of the highest overdose morbidity and mortality rates in New York City over the past decade (New York City Department of(More)
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