Brett W Hanzlicek

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We have used wild-type mice and mice possessing defects in specific retinal circuits in order to more clearly define functional circuits of the inner retina. The retina of the nob mouse lacks communication between photoreceptors and depolarizing bipolar cells (DBCs). Thus, all light driven activity in the nob mouse is mediated via remaining hyperpolarizing(More)
Childbirth injures muscles and nerves responsible for urinary continence. Mesenchymal stem cells (MSCs) or their secretome given systemically could provide therapeutic benefit for this complex multisite injury. We investigated whether MSCs or their secretome, as collected from cell culture, facilitate recovery from simulated childbirth injury. Age-matched(More)
This paper reports long-term evaluation of a micropackage technology for an implantable MEMS pressure sensor. The all-polymer micropackage survived > 160 days when subjected to accelerated lifetime testing at 85°C in a 1% wt. saline solution. The package exhibited minimum impact on sensitivity and linearity, which deviated by less than 5% and(More)
Kangli Deng, Dan Li Lin, Brett Hanzlicek, Brian Balog, Marc S. Penn, Matthew J. Kiedrowski, Zhiquan Hu, Zhangqun Ye, Hui Zhu, and Margot S. Damaser Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and(More)
Objective: Stress urinary incontinence (SUI), the leakage of urine due to an increase in abdominal pressure, affects 30% of women over the age of 40. Childbirth is the primary risk factor for SUI since the child’s head passing through the birth canal can injure the EUS and the nerve that innervates it, the pudendal nerve (PN). Animal models with combined(More)
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