Brett J. Partridge

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BACKGROUND The authors sought to characterize the pharmacologic characteristic and site of action of gabapentin (Neurontin) in a model of thermal hyperalgesia induced by intrathecal substance P administration. METHODS Rats were prepared with long-term lumbar intrathecal catheters. Hind paw withdrawal latency was determined using a radiant heat stimulus(More)
TO THE EDITOR: In a multicenter randomized trial involving 786 patients having elective total hip replacement in Canada during a 3-year period, Anderson and colleagues (1) observed how, after 10 days of dalteparin therapy, 28 days of oral aspirin prophylaxis was noninferior to 28 days of dalteparin therapy for preventing venous thromboembolism (VTE). These(More)
1] Bourreille J, Metayer P, Sauger F, et al. Existence of alpha feto protein during gastric-origin secondary cancer of the liver. Presse Medicale 1970;78: 1277–8. decrease steatosis and a 10% weight reduction is needed to improve hepatic necroinflammation. According to practice guidelines on the diagnosis and management of nonalcoholic fatty liver disease,(More)
Heterotopic pancreas is normal pancreatic tissue that lacks anatomic and vascular continuity with the main body of the pancreas. Heterotopic pancreatic tissue is a rare congenital anomaly found usually in the stomach, duodenum, or jejunum and is rarely seen in the esophagus. This is a case of heterotopic pancreas found in the esophagus that was removed(More)
Primary malignant neoplasms of the small bowel comprise only 1–3% of all gastrointestinal malignancies. Small bowel cancers pose a significant diagnostic challenge. The recent development of video capsule endoscopy (VCE) and device-assisted enteroscopy (DAE) have greatly facilitated evaluation of the small bowel. We retrospectively reviewed all cases(More)
The management of acute pancreatitis has seen many advances over the past three decades. Attempts to improve care have led to new definitions, classification systems, and treatment strategies. Despite those efforts, considerable morbidity and mortality result from complications of severe acute pancreatitis. Much attention has been given to new ways to treat(More)
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