Brent Kerbel

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BACKGROUND Nesfatin-1 is a recently discovered anorexigen encoded in the precursor peptide, nucleobindin-2 (NUCB2) in mammals. To date, nesfatin-1 has not been described in any non-mammalian species, although some information is available in the sequenced genomes of several species. Our objective was to characterize nesfatin-1 in fish. (More)
Nesfatin-1 is a novel anorectic peptide encoded in the precursor protein nucleobindin-2 (NUCB2). We recently reported the presence and appetite suppressing effects of nesfatin-1 in goldfish. Nesfatin-1 has been co-localised with ghrelin in the stomach of rats. Whether nesfatin-1 influences other appetite regulatory peptides in goldfish remains unclear. The(More)
BACKGROUND American Association of Blood Banks guidelines recommend a minimum platelet count of 50 × 10(9) /l for LPs (lumbar puncture), but evidence is lacking. The objective of this study was to describe the range of platelet counts at which LPs are performed, and the rate of traumatic taps and haemorrhagic complications in an adult oncology population.(More)
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